新着情報

2026.04.27 Achievements

2021年度　研究業績

■原著

  1. Suzuki K, Matsumaru Y, Takeuchi M, Morimoto M, Kanazawa R, Takayama Y, Kamiya Y, Shigeta K, Okubo S, Hayakawa M, Ishii N, Koguchi Y, Takigawa T, Inoue M, Naito H, Ota T, Hirano T, Kato N, Ueda T, Iguchi Y, Akaji K, Tsuruta W, Miki K, Fujimoto S, Higashida T, Iwasaki M, Aoki J, Nishiyama Y, Otsuka T, Kimura K.： SKIP Study Investigators. Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke: The SKIP Randomized Clinical Trial. JAMA. 2021 Jan 19; 325(3): 244-253.
  2. Matsuda H, Ito K, Ishii K, Shimosegawa E, Okazawa H, Mishina M, Mizumura S, Ishii K, Okita K, Shigemoto Y, Kato T, Takenaka A, Kaida H, Hanaoka K, Matsunaga K, Hatazawa J, Ikawa M, Tsujikawa T, Morooka M, Ishibashi K, Kameyama M, Yamao T, Miwa K, Ogawa M, Sato N.： Quantitative Evaluation of 18F-flutemetamol PET in Patients With Cognitive Impairment And Suspected Alzheimer’s Disease: A multicenter study: A Multicenter Study. Front Neurol. 2021 11；Article 578753.
  3. Aoki J, Iguchi Y, Urabe T, Yamagami H, Todo K, Fujimoto S, Idomari K, Kaneko N, Iwanaga T, Terasaki T, Tanaka R, Yamamoto N, Tsujino A, Nomura K, Abe K, Uno M, Okada Y, Matsuoka H, Yamagata S, Yamamoto Y, Yonehara T, Inoue T, Yagita Y, Kimura K.： ADS investigators. Cilostazol Addition to Aspirin could not Reduce the Neurological Deterioration in TOAST Subtypes: ADS Post-Hoc Analysis. J Stroke Cerebrovasc Dis. 2021 Feb;30(2):105494.
  4. Kenichi Todo, Shinichi Yoshimura, Kazutaka Uchida, Hiroshi Yamagami, Nobuyuki Sakai, Haruhiko Kishima, Hideki Mochizuki, Masayuki Ezura, Yasushi Okada, Kazuo Kitagawa, Kazumi Kimura, Makoto Sasaki, Norio Tanahashi, Kazunori Toyoda, Eisuke Furui, Yuji Matsumaru, Kazuo Minematsu, Takaya Kitano, Shuhei Okazaki, Tsutomu Sasaki, Manabu Sakaguchi, Masatoshi Takagaki, Takeo Nishida, Hajime Nakamura, Takeshi Morimoto.：RESCUE-Japan Registry 2 Investigators　Time-outcome Relationship in Acute Large-Vessel Occlusion Exists Across All Ages: Subanalysis of RESCUE-Japan Registry 2　Sci Rep. 2021 Jun 17;11(1):12782.doi: 10.1038/s41598-021-92100-7.
  5. Junya Aoki, Yasuyuki Iguchi, Takao Urabe, Hiroshi Yamagami, Kenichi Todo, Shigeru Fujimoto, Koji Idomari, Nobuyuki Kaneko, Takeshi Iwanaga, Tadashi Terasaki, Ryota Tanaka, Nobuaki Yamamoto, Akira Tsujino, Koichi Nomura, Koji Abe, Masaaki Uno, Yasushi Okada, Hideki Matsuoka, Sen Yamagata, Yasumasa Yamamoto, Toshiro Yonehara, Takeshi Inoue, Yoshiki Yagita, Kazumi Kimura.：Microbleeds and Clinical Outcome in Acute Mild Stroke Patients Treated With Antiplatelet Therapy: ADS post-hoc analysis　J Clin Neurosci. 2021 Jul;89:216-222.doi: 10.1016/j.jocn.2021.04.028.
  6. Aoki J, Sakamoto Y, Suzuki K, Nishi Y, Kutsuna A, Takei Y, Sawada K, Kanamaru T, Abe A, Katano T, Takeshi Y, Nakagami T, Numao S, Kimura R, Suda S, Nishiyama Y, Kimura K.：Fluid-Attenuated Inversion Recovery May Serve As a Tissue Clock in Patients Treated With Endovascular Thrombectomy. Stroke. 2021 Jul;52(7):2232-2240.
  7. Aoki J, Iguchi Y, Urabe T, Yamagami H, Todo K, Fujimoto S, Idomari K, Kaneko N, Iwanaga T, Terasaki T, Tanaka R, Yamamoto N, Tsujino A, Nomura K, Abe K, Uno M, Okada Y, Matsuoka H, Yamagata S, Yamamoto Y, Yonehara T, Inoue T, Yagita Y, Kimura K.：Microbleeds and Clinical Outcome in Acute Mild Stroke Patients Treated With Antiplatelet Therapy: ADS post-hoc analysis. J Clin Neurosci. 2021 Jul;89:216-222.
  8. Kaori Miwa, Masatoshi Koga, Manabu Inoue, Sohei Yoshimura, Makoto Sasaki, Yusuke Yakushiji, Mayumi Fukuda-Doi, Yasushi Okada, Taizen Nakase, Masafumi Ihara, Yoshinari Nagakane, Shunya Takizawa, Koko Asakura, Junya Aoki, Kazumi Kimura, Haruko Yamamoto, Kazunori Toyoda.：Cerebral microbleeds development after stroke thrombolysis: A secondary analysis of the THAWS randomized clinical trial Int J Stroke. 2021 Aug 3;17474930211035023. doi: 10.1177/17474930211035023.
  9. Keigo Shigeta, Kentaro Suzuki, Yuji Matsumaru, Masataka Takeuchi, Masafumi Morimoto, Ryuzaburo Kanazawa, Yohei Takayama, Yuki Kamiya, Seiji Okubo, Mikito Hayakawa, Norihiro Ishii, Yorio Koguchi, Takahiro Ota, Tomoji Takigawa, Masato Inoue, Hiromichi Naito, Teruyuki Hirano, Noriyuki Kato, Toshihiro Ueda, Kazunori Akaji, Yasuyuki Iguchi, Kazunori Miki, Wataro Tsuruta, Shigeru Fujimoto, Masaya Enomoto, Jiro Aoyama, Tomoyuki Nakano, Kazumi Kimura.：SKIP study group　Intravenous Alteplase is Associated with First Pass Effect in Stent-retriever but not ADAPT Thrombectomy : Post Hoc Analysis of the SKIP Study　Clin Neuroradiol. 2021 Sep 8. doi: 10.1007/s00062-021-01085-3.
  10. Kenichi Todo, Shinichi Yoshimura, Kazutaka Uchida, Hiroshi Yamagami, Nobuyuki Sakai, Haruhiko Kishima, Hideki Mochizuki, Masayuki Ezura, Yasushi Okada, Kazuo Kitagawa, Kazumi Kimura, Makoto Sasaki, Norio Tanahashi, Kazunori Toyoda, Eisuke Furui, Yuji Matsumaru, Kazuo Minematsu, Takaya Kitano, Shuhei Okazaki, Tsutomu Sasaki, Manabu Sakaguchi, Masatoshi Takagaki, Takeo Nishida, Hajime Nakamura, Takeshi Morimoto.：RESCUE-Japan Registry 2 Investigators　Author Correction: Time-Outcome Relationship in Acute Large-Vessel Occlusion Exists Across All Ages: subanalysis of RESCUE-Japan Registry 2　Sci Rep. 2021 Sep 8;11(1):18246. doi: 10.1038/s41598-021-97242-2.
  11. Suda S, Abe A, Iguchi Y, Yagita Y, Kanzawa T, Okubo S, Ohara N, Mizunari T, Yamazaki M, Nakajima N, Kondo K, Fujimoto S, Inoue T, Iwanaga T, Terasawa Y, Shibazaki K, Kono Y, Nakajima M, Nakajima M, Mishina M, Adachi K, Imafuku I, Nomura K, Nagao T, Yaguchi H, Okamoto S, Osaki M, Kimura K.：Characteristics of Ischemic Versus Hemorrhagic Stroke in Patients Receiving Oral Anticoagulants:　Results of the PASTA Study Intern Med. 2021 Sep 4. doi: 10.2169/internalmedicine.8113-21.
  12. Shinichiro Uchiyama, Kazunori Toyoda, Katsuhiro Omae, Ryotaro Saita, Kazumi Kimura, Haruhiko Hoshino, Nobuyuki Sakai, Yasushi Okada, Kortaro Tanaka, Hideki Origasa, Hiroaki Naritomi, Kiyohiro Houkin, Keiji Yamaguchi, Masanori Isobe, Kazuo Minematsu, Masayasu Matsumoto, Teiji Tominaga, Hidekazu Tomimoto, Yasuo Terayama, Satoshi Yasuda, Takenori Yamaguchi.：Dual Antiplatelet Therapy Using Cilostazol in Patients With Stroke and Intracranial Arterial Stenosis J Am Heart Assoc. 2021 Oct 19;10(20):e022575.doi: 10.1161/JAHA.121.022575. Epub 2021 Oct 8.
  13. Kanamaru T, Suda S, Muraga K, Ishiwata A, Aoki J, Suzuki K, Sakamoto Y, Katano T, Nishimura T, Nishiyama Y, Kimura K.：Pre-Stroke Cognitive Impairment in Acute Ischemic Stroke Patients Predicts Poor Functional Outcome After Mechanical Thrombectomy. Neurol Sci. 2021;42:4629-4635.
  14. Tetsuhiro Higashida, Ryuzaburo Kanazawa, Takanori Uchida, Yuichi Takahashi, Kentaro Suzuki, Kazumi Kimura.：Difference of Thrombus Location between Initial Noninvasive Vascular Image and First DSA Findings in Mechanical Thrombectomy for Intracranial Large Vessel Occlusion: Post Hoc Analysis of the SKIP Study　 Neurol Med Chir (Tokyo). 2021 Nov 15;61(11):640-646.doi: 10.2176/nmc.oa.2021-0137.
  15. Haruhiko Hoshino, Kazunori Toyoda, Katsuhiro Omae, Noriyuki Ishida, Shinichiro Uchiyama, Kazumi Kimura, Nobuyuki Sakai, Yasushi Okada, Kortaro Tanaka, Hideki Origasa, Hiroaki Naritomi, Kiyohiro Houkin, Keiji Yamaguchi, Masanori Isobe, Kazuo Minematsu, Masayasu Matsumoto, Teiji Tominaga, Hidekazu Tomimoto, Yasuo Terayama, Satoshi Yasuda, Takenori Yamaguchi.：CSPS.com Trial Investigators Dual Antiplatelet Therapy Using Cilostazol With Aspirin or Clopidogrel: Subanalysis of the CSPS.com Trial Stroke. 2021 Nov;52(11):3430-3439.doi: 10.1161/STROKEAHA.121.034378.
  16. Shinichi Yoshimura, Kazutaka Uchida, Nobuyuki Sakai, Hiroshi Yamagami, Manabu Inoue, Kazunori Toyoda, Yuji Matsumaru, Yasushi Matsumoto, Kazumi Kimura, Reiichi Ishikura, Takeshi Morimoto.：Randomized Clinical Trial of Endovascular Therapy for Acute Large Vessel Occlusion with Large Ischemic Core (RESCUE-Japan LIMIT): Rationale and Study Protocol Neurol Med Chir (Tokyo). 2021 Dec 24. doi: 10.2176/nmc.rc.2021-0311.
  17. Takahiro Sato, Yasuhiro Nishiyama, Satoshi Suda, Takashi Shimoyama, Shiro Takahashi, Yuki Sakamoto, Junya Aoki, Kentaro Suzuki, Tetsuro Sekine, Shin-Ichiro Kumita, Kazumi Kimura.：”Computed Tomography Perihematomal Rims”: A Perihematomal Low-Density Area Is a Part of an Acute Brain Hemorrhage Intern Med. 2021;60(15):2395-2403.doi: 10.2169/internalmedicine.6653-20.

■症例報告

  1. 青木淳哉, 鈴木健太郎, 金丸 拓也, 片野 雄大, 沓名 章仁, 西 佑治, 竹子 優歩, 中上 徹, 沼尾紳一郎, 木村龍太郎, 須田 智, 松本 典子, 西山 康裕, 木村 和美：閉塞部を通過し得た動脈硬化性内頸動脈起始部閉塞例の頸動脈エコー所見．脳卒中．2021；43: 320-326.
  2. Takuya Nishimura, Shuhei Okazaki, Hiroshi Nagayama： Visual memory recall-induced focal seizures.　A case report. Neurology and clinicalneuroscience. 2021; 9: 104-106.
  3. 小澤 明子, 山崎 峰雄, 戸田 諭輔, 江畑 琢也, 峯 清一郎, 木村 和美：　Reply from the Author　抗N-methyl-D-aspartate(NMDA)受容体脳炎後に発症した薬剤抵抗性てんかんに対して、緩和的外科的治療が有用であった2症例．臨床神経学. 2021；61(6)： 407-408.
  4. Hayashi T, Nomura K, Nishiyama Y, Kimura K：Unilateral Isolated Trochlear Nerve Palsy due to Ipsilateral Midbrain Infarction．J Nippon Med Sch．2021；88：561-563.

■総説

  1. 木村龍太郎：最新の脳卒中診断学　画像診断．診断と治療． 2021;109(5) :607-611.
  2. 西村拓哉：心原性脳塞栓症治療における左心耳閉鎖デバイスの位置付けと展望．循環器内科.  2021; 89(6): 690-696.
  3. 山崎 峰雄：認知症診断のための神経所見のとり方(No.22) 運動ニューロン疾患の診察．老年精神医学雑誌.  2021; 32(12)：1324-1330.